The Ministry of Interior said the attack on the police special unit in the provincial capital of Khost has ended with the death of seven assailants after almost nine hours on Tuesday.
The clashes began at 5:50 a.m. after a car bomb exploded and the attackers entered the compound and faced off against the Afghan security forces.
Gov. Sediq Patman said in an interview that the attackers had prepared three car bombs but two explosions were prevented by the security forces.
The initial casualties are said to be at least three people killed and 25 injured, including civilians and security personnel.